2017 Clifford Prize Presentation and Lecture - photos

2017 Clifford Prize Presentation and Lecture - photos

The Clifford Prize

The Clifford Prize, which recognises international excellence in cancer research, was awarded this year to Professor Joseph Schlessinger of Yale University, USA. Joseph spoke of the discovery of receptor tyrosine kinases and their impact on our understanding of both normal and cancer cell signaling. In a pioneering long-term effort, his group has recently identified the structure of the beta-Klotho receptor bound to its primary ligand fibroblast growth factor (FGF) 21, a cytokine that plays key roles in endocrine cell function. This information is being utilized to generate mutant FGF21 ligands with increased binding activity and efficacy for potential use in the treatment of obesity and liver disease.